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Deep-sea vent phage DNA polymerase specifically initiates DNA synthesis in the absence of primers

A DNA polymerase is encoded by the deep-sea vent phage NrS-1. NrS-1 has a unique genome organization containing genes that are predicted to encode a helicase and a single-stranded DNA (ssDNA)-binding protein. The gene for an unknown protein shares weak homology with the bifunctional primase–polymera...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhu, Bin, Wang, Longfei, Mitsunobu, Hitoshi, Lu, Xueling, Hernandez, Alfredo J., Yoshida-Takashima, Yukari, Nunoura, Takuro, Tabor, Stanley, Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373334/
https://ncbi.nlm.nih.gov/pubmed/28265063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700280114
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