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Trm5 and TrmD: Two Enzymes from Distinct Origins Catalyze the Identical tRNA Modification, m(1)G37
The N(1)-atom of guanosine at position 37 in transfer RNA (tRNA) is methylated by tRNA methyltransferase 5 (Trm5) in eukaryotes and archaea, and by tRNA methyltransferase D (TrmD) in bacteria. The resultant modified nucleotide m(1)G37 positively regulates the aminoacylation of the tRNA, and simultan...
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| Veröffentlicht in: | Biomolecules |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5372744/ https://ncbi.nlm.nih.gov/pubmed/28335556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom7010032 |
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