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Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

Colistin sulfate (polymixin E) is an antibiotic prescribed with increasing frequency for severe Gram-negative bacterial infections. As nephrotoxicity is a common side effect, the discovery of pharmacogenomic markers associated with toxicity would benefit the utility of this drug. Our objective was t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Eadon, Michael T., Hause, Ronald J., Stark, Amy L., Cheng, Ying-Hua, Wheeler, Heather E., Burgess, Kimberly S., Benson, Eric A., Cunningham, Patrick N., Bacallao, Robert L., Dagher, Pierre C., Skaar, Todd C., Dolan, M. Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372673/
https://ncbi.nlm.nih.gov/pubmed/28335481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030661
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