Genetic and epigenetic variants contributing to clofarabine cytotoxicity

2-chloro-2-fluoro-deoxy-9-D-arabinofuranosyladenine (Clofarabine), a purine nucleoside analog, is used in the treatment of hematologic malignancies and as induction therapy for stem cell transplantation. The discovery of pharmacogenomic markers associated with chemotherapeutic efficacy and toxicity...

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Bibliografske podrobnosti
Main Authors: Eadon, Michael T., Wheeler, Heather E., Stark, Amy L., Zhang, Xu, Moen, Erika L., Delaney, Shannon M., Im, Hae Kyung, Cunningham, Patrick N., Zhang, Wei, Dolan, M. Eileen
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Association Studies Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766179/
https://ncbi.nlm.nih.gov/pubmed/23720496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt240
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