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Distinct Antigen Delivery Systems Induce Dendritic Cells’ Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis

Vaccination is the most successful and cost-effective method to prevent infectious diseases. However, many vaccine antigens have poor in vivo immunogenic potential and need adjuvants to enhance immune response. The application of systems biology to immunity and vaccinology has yielded crucial insigh...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Costa, Valerio, Righelli, Dario, Russo, Francesco, De Berardinis, Piergiuseppe, Angelini, Claudia, D’Apice, Luciana
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372510/
https://ncbi.nlm.nih.gov/pubmed/28245601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030494
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