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Fluorescence based real time monitoring of fouling in process chromatography

A real time monitoring of fouling in liquid chromatography has been presented. The versatility of the approach has been proven by successful implementation in three case studies with an error <1%. The first application demonstrates the monitoring of protein A ligand density and foulant concentrat...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Pathak, Mili, Lintern, Katherine, Chopda, Viki, Bracewell, Daniel G., Rathore, Anurag S.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372471/
https://ncbi.nlm.nih.gov/pubmed/28358349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45640
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