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Fouling of an anion exchange chromatography operation in a monoclonal antibody process: Visualization and kinetic studies
Fouling of chromatographic resins over their operational lifetimes can be a significant problem for commercial bioseparations. In this article, scanning electron microscopy (SEM), batch uptake experiments, confocal laser scanning microscopy (CLSM) and small-scale column studies were applied to chara...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Publishing Ltd
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840701/ https://ncbi.nlm.nih.gov/pubmed/23483524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24898 |
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