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Separation of Oxidized Variants of a Monoclonal Antibody by Anion-Exchange
Monoclonal antibodies are subject to a variety of degradation mechanisms, therefore orthogonal techniques are required to demonstrate product quality. In this study, the three individual antibodies comprising a multi-antibody drug product, XOMA 3AB were evaluated by both cation-exchange (CEX) and an...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065544/ https://ncbi.nlm.nih.gov/pubmed/21145555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2010.10.107 |
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