Neurotrophic Factors NGF, GDNF and NTN Selectively Modulate HSV1 and HSV2 Lytic Infection and Reactivation in Primary Adult Sensory and Autonomic Neurons

Herpes simplex viruses (HSV1 and HSV2) establish latency in peripheral ganglia after ocular or genital infection, and can reactivate to produce different patterns and frequencies of recurrent disease. Previous studies showed that nerve growth factor (NGF) maintains HSV1 latency in embryonic sympathe...

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Publicado en:Pathogens
Autores principales: Yanez, Andy A., Harrell, Telvin, Sriranganathan, Heather J., Ives, Angela M., Bertke, Andrea S.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371893/
https://ncbi.nlm.nih.gov/pubmed/28178213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens6010005
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