Herpes Simplex Virus 1 Reactivates from Autonomic Ciliary Ganglia Independently from Sensory Trigeminal Ganglia To Cause Recurrent Ocular Disease

Herpes simplex virus 1 (HSV-1) and HSV-2 establish latency in sensory and autonomic neurons after ocular or genital infection, but their recurrence patterns differ. HSV-1 reactivates from latency to cause recurrent orofacial disease, and while HSV-1 also causes genital lesions, HSV-2 recurs more eff...

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Bibliographic Details
Published in:J Virol
Main Authors: Lee, Sungseok, Ives, Angela M., Bertke, Andrea S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524238/
https://ncbi.nlm.nih.gov/pubmed/26041294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00468-15
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