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Tracking the Fate and Origin of Clinically Relevant Adoptively Transferred CD8(+) T Cells In Vivo

Adoptively transferred tumor-specific cells can mediate tumor regression in cancers refractory to conventional therapy. Autologous polyclonal tumor-specific cytotoxic T cells (CTL) generated from peripheral blood and infused into patients with metastatic melanoma show enhanced persistence, compared...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Chapuis, Aude G, Desmarais, Cindy, Emerson, Ryan, Schmitt, Thomas M., Shibuya, Kendall, Lai, Ivy, Wagener, Felecia, Chou, Jeffrey, Roberts, Ilana M., Coffey, David G., Warren, Edus, Robbins, Harlan, Greenberg, Philip D., Yee, Cassian
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371351/
https://ncbi.nlm.nih.gov/pubmed/28367538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aal2568
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