Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain

In a range of animal species, exposure of the brain to general anaesthesia without surgery during early infancy may adversely affect its neural and cognitive development. The mechanisms mediating this are complex but include an increase in brain cell death. In humans, attempts to link adverse cognit...

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Vydáno v:PLoS One
Hlavní autoři: Broad, Kevin D., Kawano, Go, Fierens, Igor, Rocha-Ferreira, Eridan, Hristova, Mariya, Ezzati, Mojgan, Rostami, Jamshid, Alonso-Alconada, Daniel, Chaban, Badr, Hassell, Jane, Fleiss, Bobbi, Gressens, Pierre, Sanders, Robert D., Robertson, Nicola J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371291/
https://ncbi.nlm.nih.gov/pubmed/28355229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173413
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