Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain

In a range of animal species, exposure of the brain to general anaesthesia without surgery during early infancy may adversely affect its neural and cognitive development. The mechanisms mediating this are complex but include an increase in brain cell death. In humans, attempts to link adverse cognit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Broad, Kevin D., Kawano, Go, Fierens, Igor, Rocha-Ferreira, Eridan, Hristova, Mariya, Ezzati, Mojgan, Rostami, Jamshid, Alonso-Alconada, Daniel, Chaban, Badr, Hassell, Jane, Fleiss, Bobbi, Gressens, Pierre, Sanders, Robert D., Robertson, Nicola J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371291/
https://ncbi.nlm.nih.gov/pubmed/28355229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173413
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