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Site specific analysis of changes in the glycosylation of proteins in liver cirrhosis using data independent workflow with soft fragmentation

Cirrhosis of the liver is associated with increased fucosylation of proteins in the plasma. We describe a data independent (DIA) strategy for comparative analysis of the site-specific glycoforms of plasma glycoproteins. A library of 161 glycoforms of 25 N-glycopeptides was established by data depend...

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Bibliografiske detaljer
Udgivet i:Anal Bioanal Chem
Main Authors: Sanda, Miloslav, Zhang, Lihua, Edwards, Nathan J., Goldman, Radoslav
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370557/
https://ncbi.nlm.nih.gov/pubmed/27822650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-016-0041-8
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