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Quantitative Analysis of Immunoglobulin Subclasses and Subclass Specific Glycosylation by LC-MS-MRM in Liver Disease
Aberrant glycosylation of IgGs has been linked to human diseases, including liver disease. In this study, we have quantified plasma immunoglobulins in cirrhosis (CIR) and hepatocellular carcinoma (HCC) and employed a novel LC-MS-MRM assay to quantify glycoforms of IgG subclasses 1-4. Glycan oxonium...
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| Publicado no: | J Proteomics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329072/ https://ncbi.nlm.nih.gov/pubmed/25582524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2014.12.020 |
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