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Quantitative Analysis of Immunoglobulin Subclasses and Subclass Specific Glycosylation by LC-MS-MRM in Liver Disease

Aberrant glycosylation of IgGs has been linked to human diseases, including liver disease. In this study, we have quantified plasma immunoglobulins in cirrhosis (CIR) and hepatocellular carcinoma (HCC) and employed a novel LC-MS-MRM assay to quantify glycoforms of IgG subclasses 1-4. Glycan oxonium...

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Vydáno v:J Proteomics
Hlavní autoři: Yuan, Wei, Sanda, Miloslav, Wu, Jing, Koomen, John, Goldman, Radoslav
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329072/
https://ncbi.nlm.nih.gov/pubmed/25582524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2014.12.020
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