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Site specific analysis of changes in the glycosylation of proteins in liver cirrhosis using data independent workflow with soft fragmentation

Cirrhosis of the liver is associated with increased fucosylation of proteins in the plasma. We describe a data independent (DIA) strategy for comparative analysis of the site-specific glycoforms of plasma glycoproteins. A library of 161 glycoforms of 25 N-glycopeptides was established by data depend...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Sanda, Miloslav, Zhang, Lihua, Edwards, Nathan J., Goldman, Radoslav
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370557/
https://ncbi.nlm.nih.gov/pubmed/27822650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-016-0041-8
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