Hypermethylation of ATP‐binding cassette B1 (ABCB1) multidrug resistance 1 (MDR1) is associated with cisplatin resistance in the A549 lung adenocarcinoma cell line

Development of multiple drug resistance has been attributed to the overexpression of the ATP‐binding cassette B1 (ABCB1) gene. In this study, the major purpose was to assess the expression and methylation levels of ABCB1 in human lung adenocarcinoma and to reveal the relationship between these proce...

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Detalhes bibliográficos
Publicado no:Int J Exp Pathol
Main Authors: Li, Angui, Song, Jianfei, Lai, Qi, Liu, Bangqing, Wang, Haiyong, Xu, Yinhui, Feng, Xiaoyan, Sun, Xiaolin, Du, Zhenzong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370221/
https://ncbi.nlm.nih.gov/pubmed/27995666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12212
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