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Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma

BACKGROUND: Renal cell carcinoma patients respond poorly to conventional chemotherapy, this unresponsiveness may be attributable to multidrug resistance (MDR). The mechanisms of MDR in renal cancer are not fully understood and the specific contribution of ABC transporter proteins which have been imp...

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Detalhes bibliográficos
Main Authors: Walsh, Naomi, Larkin, Annemarie, Kennedy, Susan, Connolly, Lisa, Ballot, Jo, Ooi, Wei, Gullo, Giuseppe, Crown, John, Clynes, Martin, O'Driscoll, Lorraine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723136/
https://ncbi.nlm.nih.gov/pubmed/19552816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2490-9-6
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