Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK

Our previous study showed DNMT1 is up-regulated in esophageal squamous cell carcinoma (ESCC), which is associated with methylation of tumor suppressors. In the current study, we investigate the role of DNMT1 in ESCC. We found silencing DNMT1 inhibited proliferation, metastasis and invasion of three...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bai, Jian, Zhang, Xue, Hu, Kai, Liu, Bangqing, Wang, Haiyong, Li, Angui, Lin, Feng, Zhang, Lifei, Sun, Xiaolin, Du, Zhenzong, Song, Jianfei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190084/
https://ncbi.nlm.nih.gov/pubmed/27286455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9866
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