Silencing DNA methyltransferase 1 (DNMT1) inhibits proliferation, metastasis and invasion in ESCC by suppressing methylation of RASSF1A and DAPK

Our previous study showed DNMT1 is up-regulated in esophageal squamous cell carcinoma (ESCC), which is associated with methylation of tumor suppressors. In the current study, we investigate the role of DNMT1 in ESCC. We found silencing DNMT1 inhibited proliferation, metastasis and invasion of three...

Full description

Saved in:
Bibliographic Details
Published in:Oncotarget
Main Authors: Bai, Jian, Zhang, Xue, Hu, Kai, Liu, Bangqing, Wang, Haiyong, Li, Angui, Lin, Feng, Zhang, Lifei, Sun, Xiaolin, Du, Zhenzong, Song, Jianfei
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190084/
https://ncbi.nlm.nih.gov/pubmed/27286455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9866
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items