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Direct Targeting of Macrophages with Methylglyoxal-Bis-Guanylhydrazone Decreases SIV-Associated Cardiovascular Inflammation and Pathology
BACKGROUND: Despite effective combination antiretroviral therapy (cART) HIV infected individuals develop co-morbidities including cardiovascular disease (CVD), where activated macrophages play a key role. To date, few therapies target activated monocytes and macrophages. METHODS: We evaluated a nove...
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| Udgivet i: | J Acquir Immune Defic Syndr |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5370195/ https://ncbi.nlm.nih.gov/pubmed/28141779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001297 |
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