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Inhibition of HIV Expression and Integration in Macrophages by Methylglyoxal-Bis-Guanylhydrazone

Macrophages are a target for infection with HIV and represent one of the viral reservoirs that are relatively resistant to current antiretroviral drugs. Here we demonstrate that methylglyoxal-bis-guanylhydrazone (MGBG), a polyamine analog and potent S-adenosylmethionine decarboxylase inhibitor, decr...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Jin, Xia, McGrath, Michael S., Xu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645666/
https://ncbi.nlm.nih.gov/pubmed/26223636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01692-15
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