Direct Targeting of Macrophages with Methylglyoxal-Bis-Guanylhydrazone Decreases SIV-Associated Cardiovascular Inflammation and Pathology

BACKGROUND: Despite effective combination antiretroviral therapy (cART) HIV infected individuals develop co-morbidities including cardiovascular disease (CVD), where activated macrophages play a key role. To date, few therapies target activated monocytes and macrophages. METHODS: We evaluated a nove...

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Xehetasun bibliografikoak
Argitaratua izan da:J Acquir Immune Defic Syndr
Egile Nagusiak: Walker, Joshua A., Miller, Andrew D., Burdo, Tricia H., McGrath, Michael S., Williams, Kenneth C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370195/
https://ncbi.nlm.nih.gov/pubmed/28141779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001297
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