Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer

Niclosamide, an anthelmintic drug approved by the US Food and Drug Administration against cestodes, is used to treat tapeworm infection. In this study, we show that niclosamide can potentially inhibit signal transducer and activator of transcription 3 (STAT3) in colon cancer cell lines. Combined inh...

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Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Shi, Lingyi, Zheng, Hailun, Hu, Wanle, Zhou, Bin, Dai, Xuanxuan, Zhang, Yi, Liu, Zhiguo, Wu, Xiaoping, Zhao, Chengguang, Liang, Guang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370071/
https://ncbi.nlm.nih.gov/pubmed/28367059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S129449
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