Inhibition of STAT3 by Niclosamide Synergizes with Erlotinib against Head and Neck Cancer

Epidermal growth factor receptor (EGFR) is extensively expressed in head and neck cancer. However, EGFR-targeted therapy has only modest efficacy in head and neck cancer, through mechanisms that are not fully understood. Here, we found that inhibition of EGFR by erlotinib stimulated phosphorylation...

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Detalhes bibliográficos
Main Authors: Li, Rui, You, Shuo, Hu, Zhongliang, Chen, Zhuo G., Sica, Gabriel L., Khuri, Fadlo R., Curran, Walter J., Shin, Dong M., Deng, Xingming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760825/
https://ncbi.nlm.nih.gov/pubmed/24019973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074670
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