Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer

Niclosamide, an anthelmintic drug approved by the US Food and Drug Administration against cestodes, is used to treat tapeworm infection. In this study, we show that niclosamide can potentially inhibit signal transducer and activator of transcription 3 (STAT3) in colon cancer cell lines. Combined inh...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Shi, Lingyi, Zheng, Hailun, Hu, Wanle, Zhou, Bin, Dai, Xuanxuan, Zhang, Yi, Liu, Zhiguo, Wu, Xiaoping, Zhao, Chengguang, Liang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370071/
https://ncbi.nlm.nih.gov/pubmed/28367059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S129449
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