Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer

Niclosamide, an anthelmintic drug approved by the US Food and Drug Administration against cestodes, is used to treat tapeworm infection. In this study, we show that niclosamide can potentially inhibit signal transducer and activator of transcription 3 (STAT3) in colon cancer cell lines. Combined inh...

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Shi, Lingyi, Zheng, Hailun, Hu, Wanle, Zhou, Bin, Dai, Xuanxuan, Zhang, Yi, Liu, Zhiguo, Wu, Xiaoping, Zhao, Chengguang, Liang, Guang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370071/
https://ncbi.nlm.nih.gov/pubmed/28367059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S129449
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