Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer

Niclosamide, an anthelmintic drug approved by the US Food and Drug Administration against cestodes, is used to treat tapeworm infection. In this study, we show that niclosamide can potentially inhibit signal transducer and activator of transcription 3 (STAT3) in colon cancer cell lines. Combined inh...

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Publicado en:Onco Targets Ther
Autores principales: Shi, Lingyi, Zheng, Hailun, Hu, Wanle, Zhou, Bin, Dai, Xuanxuan, Zhang, Yi, Liu, Zhiguo, Wu, Xiaoping, Zhao, Chengguang, Liang, Guang
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370071/
https://ncbi.nlm.nih.gov/pubmed/28367059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S129449
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