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Whole-genome sequencing identifies new genetic alterations in meningiomas

The major known genetic contributor to meningioma formation was NF2, which is disrupted by mutation or loss in about 50% of tumors. Besides NF2, several recurrent driver mutations were recently uncovered through next-generation sequencing. Here, we performed whole-genome sequencing across 7 tumor-no...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Tang, Mei, Wei, Heng, Han, Lu, Deng, Jiaojiao, Wang, Yuelong, Yang, Meijia, Tang, Yani, Guo, Gang, Zhou, Liangxue, Tong, Aiping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370023/
https://ncbi.nlm.nih.gov/pubmed/28177878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15043
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