Variations within 3′-UTR of MDM4 gene contribute to clinical outcomes of advanced non-small cell lung cancer patients following platinum-based chemotherapy

Single-nucleotide polymorphism (SNPs) in microRNA (miRNA)-binding sites may modulate the posttranscriptional regulation of gene expression and explain individual sensitivity to platinum agents. This study aimed to investigate the impact of SNPs located at 3′-untranslated region (UTR) of MDM4 gene, o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Yang, Gao, Wen, Ding, Xi, Xu, Wen, Liu, Di, Su, Bo, Sun, Yifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369965/
https://ncbi.nlm.nih.gov/pubmed/27462918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10771
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