Genetic variants of BCL2 gene predict clinical outcomes of non-small-cell lung cancer patients treated with platinum-based chemotherapy in a Chinese population

Platinum agents induce cancer cell death through BCL2-dependent intrinsic apoptotic pathway and are commonly used as anti-tumor drug. In this study, we evaluated whether single nucleotide polymorphism (SNPs) of BCL2 can affect the overall survival (OS) and progression-free survival (PFS) in non-smal...

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Veröffentlicht in:Am J Cancer Res
Hauptverfasser: Ding, Xi, Qian, Ji, Yang, Yang, Xu, Wen, Liu, Di, Su, Bo
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088294/
https://ncbi.nlm.nih.gov/pubmed/27822420
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