Association of CHEK2 polymorphisms with the efficacy of platinum-based chemotherapy for advanced non-small-cell lung cancer in Chinese never-smoking women

BACKGROUND: Cell cycle checkpoint kinase 2 (CHEK2) plays an essential role in the repair of DNA damage. Single nucleotide polymorphisms (SNPs) in DNA repair genes are thought to influence treatment effects and survival of cancer patients. This study aimed to investigate the relationship between poly...

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Detalhes bibliográficos
Publicado no:J Thorac Dis
Main Authors: Xu, Wen, Liu, Di, Yang, Yang, Ding, Xi, Sun, Yifeng, Zhang, Baohong, Xu, Jinfu, Su, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059261/
https://ncbi.nlm.nih.gov/pubmed/27747004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2016.08.70
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