Sensitizing thermochemotherapy with a PARP1-inhibitor

Cis-diamminedichloroplatinum(II) (cisplatin, cDDP) is an effective chemotherapeutic agent that induces DNA double strand breaks (DSBs), primarily in replicating cells. Generally, such DSBs can be repaired by the classical or backup non-homologous end joining (c-NHEJ/b-NHEJ) or homologous recombinati...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Oei, Arlene L, Vriend, Lianne E.M, van Leeuwen, Caspar M., Rodermond, Hans M, Cate, Rosemarie ten, Westermann, Anneke M, Stalpers, Lukas J.A., Crezee, Johannes, Kanaar, Roland, Petra, Kok H., Krawczyk, Przemek M, Franken, Nicolaas A.P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369964/
https://ncbi.nlm.nih.gov/pubmed/27557507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11422
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