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In vivo histone H1 migration from necrotic to viable tissue
Necrosis is induced by ischemic conditions within the core of many solid tumors. Using fluorescent fusion proteins, we provide in vivo evidence of histone trafficking among cancer cells in implanted tumors. In particular, the most abundant H1 isoform (H1.2) was found to be transported from necrotic...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5369962/ https://ncbi.nlm.nih.gov/pubmed/28187445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15181 |
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