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In vivo histone H1 migration from necrotic to viable tissue

Necrosis is induced by ischemic conditions within the core of many solid tumors. Using fluorescent fusion proteins, we provide in vivo evidence of histone trafficking among cancer cells in implanted tumors. In particular, the most abundant H1 isoform (H1.2) was found to be transported from necrotic...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Luhrs, Keith A., Pink, Desmond, Schulte, Wendy, Zijlstra, Andries, Lewis, John D., Parseghian, Missag H.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369962/
https://ncbi.nlm.nih.gov/pubmed/28187445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15181
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