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High efficacy vasopermeability drug candidates identified by screening in an ex ovo chorioallantoic membrane model

The use of rodent models to evaluate efficacy during testing is accompanied by significant economic and regulatory hurdles which compound the costs of screening for promising drug candidates. Vasopermeation Enhancement Agents (VEAs) are a new class of biologics that are designed to increase the upta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Pink, Desmond, Luhrs, Keith A., Zhou, Longen, Schulte, Wendy, Chase, Jennifer, Frosch, Christian, Haberl, Udo, Nguyen, Van, Roy, Aparna I., Lewis, John D., Zijlstra, Andries, Parseghian, Missag H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625159/
https://ncbi.nlm.nih.gov/pubmed/26510887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15756
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