Development of a facile antibody–drug conjugate platform for increased stability and homogeneity

Despite the advances in the design of antibody–drug conjugates (ADCs), the search is still ongoing for novel approaches that lead to increased stability and homogeneity of the ADCs. We report, for the first time, an ADC platform technology using a platinum(ii)-based linker that can re-bridge the int...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Gupta, Nimish, Kancharla, Johny, Kaushik, Shelly, Ansari, Aasif, Hossain, Samad, Goyal, Ravinder, Pandey, Manoj, Sivaccumar, Jwala, Hussain, Sazid, Sarkar, Arindam, Sengupta, Aniruddha, Mandal, Swadhin K., Roy, Monideepa, Sengupta, Shiladitya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Royal Society of Chemistry 2017
Aiheet:
Chemistry
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369337/
https://ncbi.nlm.nih.gov/pubmed/28451344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc05149a
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