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Estimating genome-wide regulatory activity from multi-omics data sets using mathematical optimization

BACKGROUND: Gene regulation is one of the most important cellular processes, indispensable for the adaptability of organisms and closely interlinked with several classes of pathogenesis and their progression. Elucidation of regulatory mechanisms can be approached by a multitude of experimental metho...

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Pubblicato in:BMC Syst Biol
Autori principali: Trescher, Saskia, Münchmeyer, Jannes, Leser, Ulf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369021/
https://ncbi.nlm.nih.gov/pubmed/28347313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0419-z
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