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Estimating genome-wide regulatory activity from multi-omics data sets using mathematical optimization

BACKGROUND: Gene regulation is one of the most important cellular processes, indispensable for the adaptability of organisms and closely interlinked with several classes of pathogenesis and their progression. Elucidation of regulatory mechanisms can be approached by a multitude of experimental metho...

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Vydáno v:BMC Syst Biol
Hlavní autoři: Trescher, Saskia, Münchmeyer, Jannes, Leser, Ulf
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369021/
https://ncbi.nlm.nih.gov/pubmed/28347313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-017-0419-z
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