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Estimation of Transcription Factor Activity in Knockdown Studies

Numerous methods have been developed trying to infer actual regulatory events in a sample. A prominent class of methods model genome-wide gene expression as linear equations derived from a transcription factor (TF) – gene network and optimizes parameters to fit the measured expression intensities. W...

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書目詳細資料
發表在:Sci Rep
Main Authors: Trescher, Saskia, Leser, Ulf
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6610105/
https://ncbi.nlm.nih.gov/pubmed/31270369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46053-7
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