Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon

BACKGROUND: Chloroquine had been used extensively during the last five decades in Cameroon. Its decreasing clinical effectiveness, supported by high proportions of clinical isolates carrying the mutant pfcrt haplotype (CVIET), led the health authorities to resort to amodiaquine monotherapy in 2002 a...

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Veröffentlicht in:Malar J
Hauptverfasser: Ndam, Nicaise Tuikue, Basco, Leonardo K., Ngane, Vincent Foumane, Ayouba, Ahidjo, Ngolle, Eitel Mpoudi, Deloron, Philippe, Peeters, Martine, Tahar, Rachida
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368939/
https://ncbi.nlm.nih.gov/pubmed/28347314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1783-2
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