Use of proscribed chloroquine is associated with an increased risk of pfcrt T76 mutation in some parts of Ghana

BACKGROUND: After years of disuse of chloroquine (CQ) as first-line anti-malarial drug in Ghana, reports from molecular studies conducted in parts of the country indicate varying prevalence of T76 mutation in the pfcrt gene. This situation has several health implications, one being that mutations th...

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Autores principales: Asare, Kwame K, Boampong, Johnson N, Afoakwah, Richmond, Ameyaw, Elvis O, Sehgal, Rakesh, Quashie, Neils B
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4088365/
https://ncbi.nlm.nih.gov/pubmed/24969960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-246
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