Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon

BACKGROUND: Chloroquine had been used extensively during the last five decades in Cameroon. Its decreasing clinical effectiveness, supported by high proportions of clinical isolates carrying the mutant pfcrt haplotype (CVIET), led the health authorities to resort to amodiaquine monotherapy in 2002 a...

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Publicado en:Malar J
Autores principales: Ndam, Nicaise Tuikue, Basco, Leonardo K., Ngane, Vincent Foumane, Ayouba, Ahidjo, Ngolle, Eitel Mpoudi, Deloron, Philippe, Peeters, Martine, Tahar, Rachida
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368939/
https://ncbi.nlm.nih.gov/pubmed/28347314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1783-2
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