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The Diabetes-Linked Transcription Factor PAX4: From Gene to Functional Consequences
Paired box 4 (PAX4) is a key factor in the generation of insulin producing β-cells during embryonic development. In adult islets, PAX4 expression is sequestered to a subset of β-cells that are prone to proliferation and more resistant to stress-induced apoptosis. The importance of this transcription...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368705/ https://ncbi.nlm.nih.gov/pubmed/28282933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes8030101 |
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