Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

Heterologous prime-boosting with viral vectors encoding the pre-erythrocytic antigen thrombospondin-related adhesion protein fused to a multiple epitope string (ME-TRAP) induces CD8(+) T cell-mediated immunity to malaria sporozoite challenge in European malaria-naive and Kenyan semi-immune adults. T...

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Publicat a:Mol Ther
Autors principals: Bliss, Carly M., Drammeh, Abdoulie, Bowyer, Georgina, Sanou, Guillaume S., Jagne, Ya Jankey, Ouedraogo, Oumarou, Edwards, Nick J., Tarama, Casimir, Ouedraogo, Nicolas, Ouedraogo, Mireille, Njie-Jobe, Jainaba, Diarra, Amidou, Afolabi, Muhammed O., Tiono, Alfred B., Yaro, Jean Baptiste, Adetifa, Uche J., Hodgson, Susanne H., Anagnostou, Nicholas A., Roberts, Rachel, Duncan, Christopher J.A., Cortese, Riccardo, Viebig, Nicola K., Leroy, Odile, Lawrie, Alison M., Flanagan, Katie L., Kampmann, Beate, Imoukhuede, Egeruan B., Sirima, Sodiomon B., Bojang, Kalifa, Hill, Adrian V.S., Nébié, Issa, Ewer, Katie J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368405/
https://ncbi.nlm.nih.gov/pubmed/28153101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.11.003
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