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Specific and Efficient Regression of Cancers Harboring KRAS Mutation by Targeted RNA Replacement

Mutations in the KRAS gene, which persistently activate RAS function, are most frequently found in many types of human cancers. Here, we proposed and verified a new approach against cancers harboring the KRAS mutation with high cancer selectivity and efficient anti-cancer effects based on targeted R...

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發表在:Mol Ther
Main Authors: Kim, Sung Jin, Kim, Ju Hyun, Yang, Bitna, Jeong, Jin-Sook, Lee, Seong-Wook
格式: Artigo
語言:Inglês
出版: American Society of Gene & Cell Therapy 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368400/
https://ncbi.nlm.nih.gov/pubmed/28153088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.11.005
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