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Specific and Efficient Regression of Cancers Harboring KRAS Mutation by Targeted RNA Replacement

Mutations in the KRAS gene, which persistently activate RAS function, are most frequently found in many types of human cancers. Here, we proposed and verified a new approach against cancers harboring the KRAS mutation with high cancer selectivity and efficient anti-cancer effects based on targeted R...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Kim, Sung Jin, Kim, Ju Hyun, Yang, Bitna, Jeong, Jin-Sook, Lee, Seong-Wook
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368400/
https://ncbi.nlm.nih.gov/pubmed/28153088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.11.005
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