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KRAS Mouse Models: Modeling Cancer Harboring KRAS Mutations

KRAS is a potent oncogene and is mutated in about 30% of all human cancers. However, the biological context of KRAS-dependent oncogenesis is poorly understood. Genetically engineered mouse models of cancer provide invaluable tools to study the oncogenic process, and insights from KRAS-driven models...

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Detalles Bibliográficos
Main Authors: O’Hagan, Rónán C., Heyer, Joerg
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128636/
https://ncbi.nlm.nih.gov/pubmed/21779503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911408080
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