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NEONATAL INHIBITION OF Na(+)-K(+)-2Cl(−)-COTRANSPORTER PREVENTS KETAMINE INDUCED SPATIAL LEARNING AND MEMORY IMPAIRMENTS
Prolonged ketamine exposure in neonates at anesthetic doses is known to cause long-term impairments of learning and memory. A current theoretical mechanism explains this phenomenon as being neuro-excitotoxicity mediated by compensatory upregulation of N-methyl-D-aspartate receptors (NMDARs), which t...
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| 出版年: | Neurotoxicol Teratol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5367952/ https://ncbi.nlm.nih.gov/pubmed/27826117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ntt.2016.11.001 |
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