Neonatal ketamine exposure-induced hippocampal neuroapoptosis in the developing brain impairs adult spatial learning ability

Ketamine exposure can lead to selective neuroapoptosis in the developing brain. p(66)ShcA, the cellular adapter protein expressed selectively in immature neurons, is a known pro-apoptotic molecule that triggers neuroapoptosis when activated. Sprague-Dawley rats at postnatal day 7 were subcutaneously...

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Vydáno v:Neural Regen Res
Hlavní autoři: Lyu, Dan, Tang, Ning, Womack, Andrew W., He, Yong-Jin, Lin, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer - Medknow 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990767/
https://ncbi.nlm.nih.gov/pubmed/31719253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.268929
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