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Neonatal ketamine exposure-induced hippocampal neuroapoptosis in the developing brain impairs adult spatial learning ability

Ketamine exposure can lead to selective neuroapoptosis in the developing brain. p(66)ShcA, the cellular adapter protein expressed selectively in immature neurons, is a known pro-apoptotic molecule that triggers neuroapoptosis when activated. Sprague-Dawley rats at postnatal day 7 were subcutaneously...

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Detalhes bibliográficos
Publicado no:Neural Regen Res
Main Authors: Lyu, Dan, Tang, Ning, Womack, Andrew W., He, Yong-Jin, Lin, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990767/
https://ncbi.nlm.nih.gov/pubmed/31719253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.268929
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